Lymphomatoid papulosis in a young adult of African descent
نویسندگان
چکیده
LyP: lymphomatoid papulosis INTRODUCTION Lymphomatoid papulosis (LyP) is an indolent skin disease characterized by chronic, recurrent, selfhealing papules and nodules with histologic findings suggestive of malignant lymphoma. LyP is classified as a CD301 cutaneous lymphoproliferative disorder according to the 2005 World Health Organization/ European Organisation for Research and Treatment of Cancer classification and has 5 histologic subtypes (A-E). Differential diagnoses of LyP includes other CD30 cutaneous lymphomas, systemic T-cell or Bcell lymphomas, and reactive processes that exhibit CD30 expression. LyP rarely affects black skin, with only 2 previously reported cases. We present a case of LyP in a male of African descent.
منابع مشابه
[Lymphomatoid papulosis in children: report of 9 cases and review of the literature].
BACKGROUND Lymphomatoid papulosis is a rare lymphoproliferative T cell CD30+ disease with excellent prognosis which affects almost exclusively adult patients, being rarely in the childhood; thus the clinic and pathologic spectrum and the risk of evolution to another type of lymphoma are not well defined in the pediatric group. OBJECTIVE The aim of this article is to analyze the characteristic...
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We present two cases of childhood and one case of adult Lymphomatoid papulosis (LyP), an entity which is commonly misdiagnosed and poorly described in the paediatric dermatology literature. Clinically and histologically, the features of LyP in children can mimic insect bite reaction, with prominent dermal neutrophils and eosinophils. However, CD30 immunohistochemical staining of atypical lympho...
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Lymphomatoid papulosis is a cutaneous lymphoma with an indolent clinical behaviour characterized by chronic development of recurrent, self-limited lesions appearing as necrotic papules and with a pathology compatible with T cell lymphoma. Mucosal involvement by lymphomatoid papulosis is very rare but has been reported in the literature. It usually appears as ulcers in patients previously diagno...
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